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1

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism

James, S Jill, Cutler, Paul, Melnyk, Stepan, Jernigan, Stefanie, Janak, Laurette, Gaylor, David W, Neubrander, James A

Journal:

American Journal of Clinical Nutrition

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

2

Abnormal Transmethylation/transsulfuration Metabolism and DNA Hypomethylation Among Parents of Children with Autism

S. Jill James, Stepan Melnyk, Stefanie Jernigan, Amanda Hubanks, Shannon Rose, David W. Gaylor

Journal:

Journal of Autism and Developmental Disorders

Year:

2008

Language:

english

File:

PDF, 82 KB

english, 2008

3

Metabolic Imbalance Associated with Methylation Dysregulation and Oxidative Damage in Children with Autism

Stepan Melnyk, George J. Fuchs, Eldon Schulz, Maya Lopez, Stephen G. Kahler, Jill J. Fussell, Jayne Bellando, Oleksandra Pavliv, Shannon Rose, Lisa Seidel, David W. Gaylor, S. Jill James

Journal:

Journal of Autism and Developmental Disorders

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

4

Experimental Design of Bioassays for Screening and Low Dose Extrapolation

David W. Gaylor, James J. Chen, Ralph L. Kodell

Journal:

Year:

1985

Language:

english

File:

PDF, 578 KB

english, 1985

5

Final Report of the Color Additive Scientific Review Panel

Ronald W. Hart, Stan C. Freni, David W. Gaylor, James R. Gillette, Larry K. Lowry, Jerrold M. Ward, Elizabeth K. Weisburger, Paul Lepore, Angelo Turturro

Journal:

Year:

1986

Language:

english

File:

PDF, 3.21 MB

english, 1986

6

Relative Potency of Chemical Carcinogens in Rodents

David W. Gaylor, James J. Chen

Journal:

Year:

1986

Language:

english

File:

PDF, 570 KB

english, 1986

7

Using Average Lifetime Dose Rate for Intermittent Exposures to Carcinogens

Ralph L. Kodell, David W. Gaylor, James J. Chen

Journal:

Year:

1987

Language:

english

File:

PDF, 450 KB

english, 1987

8

Using the Biological Two-Stage Model to Assess Risk from Short-Term Exposures

James J. Chen, Ralph L. Kodell, David W. Gaylor

Journal:

Year:

1988

Language:

english

File:

PDF, 505 KB

english, 1988

9

Uncertainty in Cancer Risk Estimates

David W. Gaylor, James J. Chen, Daniel M. Sheehan

Journal:

Year:

1993

Language:

english

File:

PDF, 563 KB

english, 1993

10

A Simple Upper Limit for the Sum of the Risks of the Components in a Mixture

David W. Gaylor, James J. Chen

Journal:

Year:

1996

Language:

english

File:

PDF, 331 KB

english, 1996

11

Dose-dependent transitions in mechanisms of toxicity: case studies

William Slikker Jr., Melvin E. Andersen, Matthew S. Bogdanffy, James S. Bus, Steven D. Cohen, Rory B. Conolly, Raymond M. David, Nancy G. Doerrer, David C. Dorman, David W. Gaylor, Dale Hattis, John M

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 2.52 MB

english, 2004

12

Dose-dependent transitions in mechanisms of toxicity

William Slikker Jr., Melvin E. Andersen, Matthew S. Bogdanffy, James S. Bus, Steven D. Cohen, Rory B. Conolly, Raymond M. David, Nancy G. Doerrer, David C. Dorman, David W. Gaylor, Dale Hattis, John M

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 421 KB

english, 2004

13

Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism

James, S. J., Rose, S., Melnyk, S., Jernigan, S., Blossom, S., Pavliv, O., Gaylor, D. W.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 395 KB

english, 2009

14

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome

James, S Jill, Pogribna, Marta, Pogribny, Igor P, Melnyk, Stepan, Hine, R Jean, Gibson, James B, Yi, Ping, Tafoya, Dixie L, Swenson, David H, Wilson, Vincent L, Gaylor, David W

Journal:

American Journal of Clinical Nutrition

Year:

1999

Language:

english

File:

PDF, 217 KB

english, 1999

15

DOSE-RESPONSE MODELLING OF GROWTH FOR DEVELOPMENTAL TOXICITY

JAMES J. CHEN, DAVID W. GAYLOR, JAMES B. LABORDE

Journal:

Year:

1996

Language:

english

File:

PDF, 662 KB

english, 1996

16

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism

S. Jill James, Stepan Melnyk, Stefanie Jernigan, Mario A. Cleves, Charles H. Halsted, Donna H. Wong, Paul Cutler, Kenneth Bock, Marvin Boris, J. Jeffrey Bradstreet, Sidney M. Baker, David W. Gaylor

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

17

A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism

S. Jill James, Stepan Melnyk, Stefanie Jernigan, Oleksandra Pavliv, Timothy Trusty, Sara Lehman, Lisa Seidel, David W. Gaylor, Mario A. Cleves

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2010

Language:

english

File:

PDF, 263 KB

english, 2010

18

A simplified assay of 4-methyl sterol oxidase of liver microsomes

Donald R. Brady, Thomas W. Mattingly, James L. Gaylor

Journal:

Analytical Biochemistry

Year:

1976

Language:

english

File:

PDF, 599 KB

english, 1976

19

In vitro investigation of the blood response to medical grade PVC and the effect of heparin on the blood response

Nina M.K Lamba, James M Courtney, John D.S Gaylor, Gordon D.O Lowe

Journal:

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

20

Multisorbent Plasma Perfusion in Fulminant Hepatic Failure: Effects of Duration and Frequency of Treatment in Rats with Grade III Hepatic Coma

Calvin J. Ryan, Thapasimuthu Anilkumar, Abdul J.A. Ben-Hamida, Shirin E. Khorsandi, Mohammed Aslam, Charles D. Pusey, John D.S. Gaylor, James M. Courtney

Journal:

Artificial Organs

Year:

2001

Language:

english

File:

PDF, 537 KB

english, 2001

21

Chromatographic techniques for rapid measurement of gel in elastomers

V. F. Gaylor, H. L. James, J. P. Herdering

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1975

Language:

english

File:

PDF, 602 KB

english, 1975

22

Abnormal Transmethylation/transsulfuration Metabolism and DNA Hypomethylation Among Parents of Children with Autism

S. Jill James, Stepan Melnyk, Stefanie Jernigan, Amanda Hubanks, Shannon Rose, David W. Gaylor

Journal:

Journal of Autism and Developmental Disorders

Year:

2008

Language:

english

File:

PDF, 439 KB

english, 2008

23

CELL LAYER AND DENSITY OF NEGRO AND CAUCASIAN STRATUM CORNEUM.

Weigand, Dennis Allen, Haygood, Carl, Gaylor, James R.

Journal:

The Journal of Investigative Dermatology

Year:

1974

File:

PDF, 943 KB

1974

24

REMOVAL OF STRATUM CORNEUM IN VIVO: AN IMPROVEMENT ON THE CELLOPHANE TAPE STRIPPING TECHNIQUE.

Weigand, Dennis A., Gaylor, James R.

Journal:

The Journal of Investigative Dermatology

Year:

1973

File:

PDF, 1.49 MB

1973

25

Estimation of the Joint Risk from Multiple-Compound Exposure Based on Single-Compound Experiments

James J. Chen, David W. Gaylor, Ralph L. Kodell

Journal:

Year:

1990

Language:

english

File:

PDF, 459 KB

english, 1990

26

Reply to T. R. Auton's Letter to the Editor

James J. Chen, David W. Gaylor, Ralph L. Kodell

Journal:

Year:

1991

File:

PDF, 38 KB

1991

27

Mathematical Modeling of Reproductive and Developmental Toxic Effects for Quantitative Risk Assessment

Ralph L. Kodell, Richard B. Howe, James J. Chen, David W. Gaylor

Journal:

Year:

1991

Language:

english

File:

PDF, 633 KB

english, 1991

28

Point Estimates of Cancer Risk at Low Doses

David W. Gaylor, Ralph L. Kodell, James J. Chen, Janet A. Springer, Ronald J. Lorentzen, Robert J. Scheuplein

Journal:

Year:

1994

Language:

english

File:

PDF, 592 KB

english, 1994

29

Ultraviolet-Induced Individual Cell Keratinization

Robert L. Olson, James Gaylor, MarkA. Everett

Journal:

Journal of Cutaneous Pathology

Year:

1974

Language:

english

File:

PDF, 4.08 MB

english, 1974

30

Correlations of developmental end points observed after 2,4,5-trichlorophenoxyacetic acid exposure in mice

James J. Chen, David W. Gaylor

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1992

Language:

english

File:

PDF, 544 KB

english, 1992

31

Dose-response models for developmental malformations

David W. Gaylor, James J. Chen

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1993

Language:

english

File:

PDF, 586 KB

english, 1993

32

Microsomal enzymes of cholesterol biosynthesis from lanosterol: A progress report

James M. Trazaskos, Wayne D. Bowen, Gary J. Fisher, Jeffrey T. Billheimer, James L. Gaylor

Journal:

Year:

1982

Language:

english

File:

PDF, 637 KB

english, 1982

33

INVESTIGATION OF THE MULTIENZYMIC SYSTEM OF MICROSOMAL CHOLESTEROL BIOSYNTHESIS

James L. Gaylor, Constance V. Delwiche

Journal:

Annals of the New York Academy of Sciences

Year:

1973

Language:

english

File:

PDF, 853 KB

english, 1973

34

Repeated Membrane Plasma Separation with On-Line Sorbent Treatment of Plasma in the Conscious Rat

Calvin J. Ryan, Charles D. Pusey, Mohammed Aslam, John D. S. Gaylor, Roshan Maini, James M. Courtney

Journal:

Artificial Organs

Year:

1986

Language:

english

File:

PDF, 905 KB

english, 1986

35

Blood-Contacting Biomaterials: Bioengineering Viewpoints

James M. Courtney, Nina M.K. Lamba, John D.S. Gaylor, Calvin J. Ryan, Gordon D.O. Lowe

Journal:

Artificial Organs

Year:

1995

Language:

english

File:

PDF, 429 KB

english, 1995

36

Membrane-Bound Enzymes of Cholesterol Synthesis from Lanosterol

James L. Gaylor

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

37

Estimating the Probability of Occurrence of Tumor for a Rare Cancer with Zero Occurrence in a Sample

Asit P. Basu, David W. Gaylor, James J. Chen

Journal:

Regulatory Toxicology and Pharmacology

Year:

1996

Language:

english

File:

PDF, 119 KB

english, 1996

38

Precision of Benchmark Dose Estimates for Continuous (Nonquantal) Measurements of Toxic Effects

David W. Gaylor, James J. Chen

Journal:

Regulatory Toxicology and Pharmacology

Year:

1996

Language:

english

File:

PDF, 107 KB

english, 1996

39

A Unified Approach to Risk Assessment for Cancer and Noncancer Endpoints Based on Benchmark Doses and Uncertainty/Safety Factors1

David W. Gaylor, Ralph L. Kodell, James J. Chen, Daniel Krewski

Journal:

Regulatory Toxicology and Pharmacology

Year:

1999

Language:

english

File:

PDF, 57 KB

english, 1999

40

Human Cancer Risk Estimates Are Reduced When Based on Relative Risk for Common Rodent Tumors

David W. Gaylor, Ralph L. Kodell, James J. Chen

Journal:

Regulatory Toxicology and Pharmacology

Year:

1999

Language:

english

File:

PDF, 59 KB

english, 1999

41

Solubilization and partial purification of a microsomal 3-ketosteroid reductase of cholesterol biosynthesis

Jeffrey T. Billheimer, Mary Alcorn, James L. Gaylor

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 818 KB

english, 1981

42

Cytosolic modulators of activities of microsomal enzymes of cholesterol biosynthesis purification and characterization of a non-specific lipid-transfer protein

James M. Trzaskos, James L. Gaylor

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 1.41 MB

english, 1983

43

Effect of lipid composition on the transfer of sterols mediated by non-specific lipid transfer protein (sterol carrier protein2)

Jeffrey T. Billheimer, James L. Gaylor

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1990

Language:

english

File:

PDF, 936 KB

english, 1990

44

Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 14-reductase

Chap-Ki Kim, Kye-Im Jeon, Dong-Min Lim, Tae-Neung Johng, James M. Trzaskos, James L. Gaylor, Young-Ki Paik

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 874 KB

english, 1995

45

Two methods provide similar signals for the need to update systematic reviews

Mei Chung, Sydne J. Newberry, Mohammed T. Ansari, Winifred W. Yu, Helen Wu, Jounghee Lee, Marika Suttorp, James M. Gaylor, Aneesa Motala, David Moher, Ethan M. Balk, Paul G. Shekelle

Journal:

Journal of Clinical Epidemiology

Year:

2012

Language:

english

File:

PDF, 182 KB

english, 2012

46

A comparison of microbial dose–response models fitted to human data

Hojin Moon, James J. Chen, David W. Gaylor, Ralph L. Kodell

Journal:

Regulatory Toxicology and Pharmacology

Year:

2004

Language:

english

File:

PDF, 330 KB

english, 2004

47

An overused phrase: interpreted with caution

Gaylor, James M.

Journal:

Journal of Clinical Epidemiology

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

48

Further characterization of the 5α-hydroxysterol dehydrase of yeast

Richard W. Topham, James L. Gaylor

Journal:

Biochemical and Biophysical Research Communications

Year:

1972

Language:

english

File:

PDF, 332 KB

english, 1972

49

Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties

Trzaskos, James M., Ko, Soo S., Magolda, Ronald L., Favata, Margaret F., Fischer, Robert T., Stam, Simon H., Johnson, Paul R., Gaylor, James L.

Journal:

Year:

1995

Language:

english

File:

PDF, 905 KB

english, 1995

50

Intraocular Lens Disasters

Rowsey, J. James, Gaylor, James A.

Journal:

Year:

1980

Language:

english

File:

PDF, 17.96 MB

english, 1980